암치료
암 치료에서의 기회: p53-MDM2/MDMX 상호작용을 표적으로 함
unicircle
2022. 11. 25. 16:36
2021
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8727821/
Therapeutic opportunities in cancer therapy: targeting the p53-MDM2/MDMX interactions
Ubiquitination is a key enzymatic post-translational modification that influences p53 stability and function. p53 protein regulates the expression of MDM2 (mouse double-minute 2 protein) E3 ligase and MDMX (double-minute 4 protein), through proteasome-base
www.ncbi.nlm.nih.gov
Therapeutic opportunities in cancer therapy: targeting the p53-MDM2/MDMX interactions
MDMX 상호 작용 및 p53의 전사 억제를 나타내는 개략도.