열리라

https://file.selleckchem.com/publicity/Selleck-Inhibitor-Catalog-Low-Resolution-EN.pdf cell signaling pathways Inhibitor catalog

2005 https://www.ibric.org/myboard/read.php?Board=news&id=99694 p53와 AMPK 활성화를 우회하여 암세포는 계속 증식 미국 펜실베니아 의대 (University of Pennsylvania School of Medicine) 의 Craig Th... www.ibric.org p53와 AMPK 활성화를 우회하여 암세포는 계속 증식 이번 연구 결과는 학술지 “Molecular Cell “ 에 발표되었다. 이번 연구는 세포의 정상적 능력을 초과하여 증식하기 위해 대사를 조절하는 세포적 대사 경로를 암세포가 가지고 있다는 새로운 개념을 시험하는 것이었다. 암 세포는 높은 대사율을 가지고 높은 비율의 당을 소비한다. 이번 연구에서 시험된 기본적인 질문은 암에서의..

2020 https://www.dovepress.com/hif-1alpha-is-a-potential-molecular-target-for-herbal-medicine-to-trea-peer-reviewed-fulltext-article-DDDT# HIF-1α is a Potential Molecular Target for Herbal Medicine to Tr | DDDT HIF-1α is a Potential Molecular Target for Herbal Medicine to Treat Diseases www.dovepress.com HIF-1α is a Potential Molecular Target for Herbal Medicine to Treat Diseases ***************..

2021 https://www.mdpi.com/2072-6694/13/11/2813/htm An Overview of the Recent Development of Anticancer Agents Targeting the HIF-1 Transcription Factor Hypoxia, a characteristic feature of solid tumors, is associated with the malignant phenotype and therapy resistance of cancers. Hypoxia-inducible factor 1 (HIF-1), which is responsible for the metazoan adaptive response to hypoxia, has been recog..

2016 https://www.sciencedirect.com/science/article/pii/S0163725816300559 Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer Insufficient tissue oxygenation, or hypoxia, contributes to tumor aggressiveness and has a profound impact on clinical outcomes in cancer patients. At… www.sciencedirect.com Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer 그림 2...

2022 https://www.frontiersin.org/articles/10.3389/fgene.2022.849040/full Therapeutic Targeting Hypoxia-Inducible Factor (HIF-1) in Cancer: Cutting Gordian Knot of Cancer Cell Metabolism Metabolic alterations are one of the hallmarks of cancer, which has recently gained great attention. Increased glucose absorption and lactate secretion in cancer cells are characterized by the Warburg effect, whi..

2005 PDF Resveratrol inhibits hypoxia-induced accumulation of hypoxia-inducible factor-1A and VEGF expression in human tongue squamous cell carcinoma and hepatoma cells 레스베라트롤 사용의 주요 관심사 중 하나는 고용량에서 잠재적인 독성입니다. 대부분의 시험관 내 연구에서 레스베라트롤은 5~100umol/L 범위의 농도로 사용되었습니다. 일반적으로 테스트된 대부분의 시스템에서 세포사멸 효과가 나타난 용량은 세포 주기 정지 또는 세포 증식 억제를 유도하는 데 사용된 용량(10 – 30 umol/L)보다 상대적으로 더 높습니다(100 – 300 umol/L). 최근 Tseng ..

2010 https://bmccancer.biomedcentral.com/articles/10.1186/1471-2407-10-143 Potent inhibition of tumoral hypoxia-inducible factor 1α by albendazole - BMC Cancer Background Emerging reports suggest resistance, increased tumor invasiveness and metastasis arising from treatment with drugs targeting vascular endothelial growth factor (VEGF). It is believed that increased tumoral hypoxia plays a promi..

2022 https://www.sciencedirect.com/science/article/abs/pii/S1044579X20302029 Targeting hypoxia-inducible factor-1, for cancer treatment: Recent advances in developing small-molecule inhibitors from natural Rapid progress in molecular cancer biology coupled with the discovery of novel oncology drugs has opened new horizons for cancer target discovery. As … www.sciencedirect.com Targeting hypoxia-..

https://blog.naver.com/ymgilman/222196779936 암의 비정상 신호 스위치 6, NGS 검사와 암 대사에 영향을 주는 주요 유전자 신호 [아주 아주 쉬운 안녕하세요~ 요즘 카페 게시판에 보면 NGS 결과 판독을 요청해 주시는 분들이 많습니다. 병원에서 검사... blog.naver.com