허브-약물 상호작용

https://www.nature.com/articles/s41598-019-41532-3#Fig4

<potential herb-drug interactions>

Figure 4

From: Complementary medicine use during cancer treatment and potential herb-drug interactions from a cross-sectional study in an academic centre

Table of potential pharmacokinetic interactions between herbal medicines and anticancer agents. Properties of herbal medicines in metabolic/transport pathways: Red = inhibition, green = induction, violet = controversial in references (inhibition and/or induction), blue: metabolic/transporter pathway, italic blue = metabolic pathway leading to a major active metabolite; 3A4 = cytochrome P450 3A4 (etc.); P-gp = P-glycoprotein; OCT = organic cation transport; DPD = dihydropyrimidine dehydrogenase. References used to build the table can be found online in Supplementary Data S3 and Supplementary Table S4.

 

빨간색 = 억제,

녹색 = 유도,

보라색 = 참고문헌(억제 및/또는 유도)에서 논란의 여지가 있음,

파란색: 대사/수송체 경로,

이탤릭체 파란색 = 주요 활성 대사체로 이어지는 대사 경로