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https://www.mdpi.com/1420-3049/25/22/5319/htm Plant-Derived Natural Products in Cancer Research: Extraction, Mechanism of Action, and Drug Formulation Cancer is one of the main causes of death globally and considered as a major challenge for the public health system. The high toxicity and the lack of selectivity of conventional anticancer therapies make the search for alternative treatments a pr..

https://www.mdpi.com/2076-3921/10/1/83/htm Role of Phytochemicals in Perturbation of Redox Homeostasis in Cancer Over the past few decades, research on reactive oxygen species (ROS) has revealed their critical role in the initiation and progression of cancer by virtue of various transcription factors. At certain threshold values, ROS act as signaling molecules leadin www.mdpi.com 3. 파이토케미칼: ROS ..

Autophagy modulation as a potential therapeutic target for diverse diseases Table 2 Selected drugs and compounds that modulate autophagy CompoundsCompanyStructureMechanism of actionRefs Autophagy inducers Rapamycin Sigma-Aldrich Induces autophagy by inhibiting mTORC1 44,49, 246 PP242 Sigma-Aldrich Induces autophagy by inhibiting mTORC1 247 Torin 1 Tocris Bioscience Directly inhibits both mTORC1 ..

Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine https://cmjournal.biomedcentral.com/articles/10.1186/s13020-019-0270-9 Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine - Chinese Medicine Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer activities, including anti-proliferative, pro-apoptotic, anti-..

http://neuroimaging.snu.ac.kr/adm_mgr/board/bbs_download.php?st_id=&pm_id=7&wr_id=200&wf_id=1 --다른 이름으로 링크저장

Building an off-label drugs protocol for cancer? https://www.canceractive.com/article/an-offlabel%20drugs%20protocol%20for%20cancer Building an off-label drugs protocol for cancer? | CANCERactive Using off-label drugs in an anti-cancer protocol is a hot topic among cancer patients and here is a practical guide of the top repurposed drugs being used by patients to help fight their cancer, alongsi..

Drug rechanneling: A novel paradigm for cancer treatment https://www.sciencedirect.com/science/article/pii/S1044579X20300778 Drug rechanneling: A novel paradigm for cancer treatment Cancer continues to be one of the leading contributors towards global disease burden. According to NIH, cancer incidence rate per year will increase t… www.sciencedirect.com

Repurposing approved drugs on the pathway to novel therapies https://onlinelibrary.wiley.com/doi/full/10.1002/med.21627 Repurposing approved drugs on the pathway to novel therapies The time and cost of developing new drugs have led many groups to limit their search for therapeutics to compounds that have previously been approved for human use. Many “repurposed” drugs, such as d... onlinelibrary...

New drugs are not enough‑drug repositioning in oncology: An update https://www.spandidos-publications.com/10.3892/ijo.2020.4966 New drugs are not enough‑drug repositioning in oncology: An update Drug repositioning refers to the concept of discovering novel clinical benefits of drugs that are already known for use treating other diseases. The advantages of this are that several important drug cha..

Epidrug Repurposing: Discovering New Faces of Old Acquaintances in Cancer Therapy https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7708379/ Figure 1 Overview of the epigenetic landscape. Different compaction levels of chromatin are depicted, from naked DNA to the metaphasic chromosome. (A) Two dimers of H2A-H2B and a tetramer of H3-H4 histones are required for nucleosome assembly, the chromatin’s ba..