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https://www.mdpi.com/1420-3049/25/22/5319/htm Plant-Derived Natural Products in Cancer Research: Extraction, Mechanism of Action, and Drug Formulation Cancer is one of the main causes of death globally and considered as a major challenge for the public health system. The high toxicity and the lack of selectivity of conventional anticancer therapies make the search for alternative treatments a pr..

https://www.mdpi.com/1422-0067/19/11/3568/htm Targeting Cancer with Phytochemicals via Their Fine Tuning of the Cell Survival Signaling Pathways The role of phytochemicals as potential prodrugs or therapeutic substances against tumors has come in the spotlight in the very recent years, thanks to the huge mass of encouraging and promising results of the in vitro activity of many phenolic compound..

https://www.mdpi.com/1422-0067/21/2/401/htm Alleviation of Multidrug Resistance by Flavonoid and Non-Flavonoid Compounds in Breast, Lung, Colorectal and Prostate Cancer The aim of the manuscript is to discuss the influence of plant polyphenols in overcoming multidrug resistance in four types of solid cancers (breast, colorectal, lung and prostate cancer). Effective treatment requires the use of ..

https://www.mdpi.com/2076-3921/10/1/83/htm Role of Phytochemicals in Perturbation of Redox Homeostasis in Cancer Over the past few decades, research on reactive oxygen species (ROS) has revealed their critical role in the initiation and progression of cancer by virtue of various transcription factors. At certain threshold values, ROS act as signaling molecules leadin www.mdpi.com 3. 파이토케미칼: ROS ..

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758087/ Summary of some major functional foods, their biological effects and signaling mechanisms Food Functional compound Biological function Signaling pathways or mechanismsReference Ginger Ginger extract Anti-obesity/Anti-inflammatory ↑ PPAR-δ 42 Gingerols Anti-inflammatory ↓ PGEs, COX1&2, lipoxygenase, leukotrienes, PG synthetase 43, 45 Zingerone..

Chap.2 Targeting Cancer Metabolism and Current Anti-Cancer Drugs

https://www.researchgate.net/profile/Javier-Menendez-2/publication/319883404_Fatty_Acid_Synthase_FASN_as_a_therapeutic_target_in_breast_cancer/links/59c8d778a6fdccc71929c484/Fatty-Acid-Synthase-FASN-as-a-therapeutic-target-in-breast-cancer.pdf 2017년 1세대 FASN 억제제: 약속보다 더 많은 함정 2.1. Cerulenin and C75 그림 1. 유방암에서 FASN의 대사-종양 발생 특성: 유방암 세포는 FASN 신호전달의 과활성화를 포함하여 비정상적인 대사 표현형을 유지하는 데 있어 증가하는 자율성을 나타낼..

https://academic.oup.com/pcm/article/2/3/183/5579809?login=true expanded role of fatty acid metabolism in cancer: new aspects and targets Abstract. Cancer cells undergo metabolic reprogramming to support cell proliferation, growth, and dissemination. Alterations in lipid metabolism, and specifical academic.oup.com The expanded role of fatty acid metabolism in cancer: new aspects and targets 2019..

https://www.mdpi.com/2072-6643/11/11/2799/htm Precision Nutrition and Cancer Relapse Prevention: A Systematic Literature Review Cancer mortality rates are undergoing a global downward trend; however, metastasis and relapse after surgery and adjuvant treatments still correlate with poor prognosis and represent the most significant challenges in the treatment of this disease. Advance www.mdpi.com ..

https://www.mdpi.com/1420-3049/26/12/3494/htm# Natural Compounds as Metabolic Modulators of the Tumor Microenvironment The tumor microenvironment (TME) is a heterogenous assemblage of malignant and non-malignant cells, including infiltrating immune cells and other stromal cells, together with extracellular matrix and a variety of soluble factors. This complex and dynamic m www.mdpi.com Natural C..