열리라

2011 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252717/ Patient Counseling about Herbal-Drug Interactions 약초는 하나 이상의 활성 성분의 혼합물입니다. 다수의 약리학적 활성 화합물은 상호작용이 일어날 가능성을 분명히 증가시킵니다. 따라서 합성 약물은 일반적으로 단일 화학 물질을 포함하기 때문에 허브-약물 상호 작용의 가능성은 이론적으로 약물-약물 상호 작용보다 높습니다. 허브와 약물은 약동학적 또는 약력학적으로 상호 작용할 수 있습니다. 이 상호작용의 주된 메커니즘은 소장에서 시토크롬 P-450 3A4의 억제입니다. 약물 presystemic 대사의 상당한 감소를 초래합니다. 추가 메커니즘은 장세포에서 장내강으로 약..

2012 https://www.frontiersin.org/articles/10.3389/fphar.2012.00069/full An overview of the evidence and mechanisms of herb–drug interactions 허브-약물 상호작용의 증거 및 메커니즘 개요 An Overview of the Evidence and Mechanisms of Herb–Drug Interactions Despite the lack of sufficient information on the safety of herbal products, their use as alternative and/or complementary medicine is globally popular. There is a..

2021 Multifaceted Factors Causing Conflicting Outcomes in Herb-Drug Interactions https://www.mdpi.com/1999-4923/13/1/43/htm Multifaceted Factors Causing Conflicting Outcomes in Herb-Drug Interactions Metabolic enzyme and/or transporter-mediated pharmacokinetic (PK) changes in a drug caused by concomitant herbal products have been a primary issue of herb and drug interactions (HDIs), because PK c..

약물 상호 작용의 메커니즘 2020 https://nmiccomms.newsweaver.com/izn877i20c/f4c8imyv8y6 Drug Interactions (1): General Principles The clinical significance of an interaction depends on patient (e.g. age and co-morbidities) and drug factors including the therapeutic index of the drug, the potency and concentration of the interacting drug and the clearance system of the drug (e.g. the nmiccomms.newsweaver.com..

2021 https://fjps.springeropen.com/articles/10.1186/s43094-021-00256-w Current perspectives in herbal and conventional drug interactions based on clinical manifestations - Future Journal of Pharmaceu Background Herbs are an important source of pharmaceuticals. Herbs are traditionally used by millions of peoples for medicine, food and drink in developed and developing nations considering that the..

2016 HERB-DRUG INTERACTIONS: AN OVERVIEW OF MECHANISMS AND CLINICAL ASPECTS http://ijpsr.com/bft-article/herb-drug-interactions-an-overview-of-mechanisms-and-clinical-aspects/?view=fulltext 2.허브-약물 상호작용과 관련된 메커니즘: 약초-약물 상호작용은 관련된 기전에 따라 약동학적 상호작용과 약력학적 상호작용으로 분류됩니다. 2.1 약동학적 상호작용: 약동학적 상호작용은 약물의 흡수, 분포, 대사 또는 배설의 변화에 ​​의해 유발되어 약물 또는 그 대사물의 수준이 변경됩니다. 2.1.1 흡수 수준에서 허브-약물 상호작용 2.1.1.1 efflux trans..

2019 Understanding the relevance of herb–drug interaction studies with special focus on interplays: a prerequisite for integrative medicine (상호 작용에 특별한 초점을 맞춘 허브-약물 상호 작용 연구의 관련성 이해: 통합 의학의 전제 조건) https://europepmc.org/article/pmc/pmc6726296 Understanding the relevance of herb-drug interaction studies with special focus on interplays: a prerequisite for integrative me Abstract Integrative medici..

https://ars.els-cdn.com/content/image/3-s2.0-B978032398367900010X-f13-03-9780323983679.jpg https://ars.els-cdn.com/content/image/1-s2.0-B9780444641793000098-f09-01-9780444641793.jpg https://www.knowledgedose.com/drugs-undergoing-extensive-first-pass-metabolism/ Drugs Undergoing Extensive First-Pass Metabolism | KnowledgeDose Some drugs that are administered via the oral route undergo extensive f..

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2021 https://www.sciencedirect.com/science/article/abs/pii/S0278691521004658 Herb-drug interactions and toxicity: Underscoring potential mechanisms and forecasting clinically relevant interactions induced Herbals in the form of medicine are employed extensively around the world. Herbal and conventional medicine combination is a potentially dangerous pra… www.sciencedirect.com Herb-drug interacti..