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2019 https://stemcellsjournals.onlinelibrary.wiley.com/doi/full/10.1002/stem.3101 Aberrant lipid metabolism as an emerging therapeutic strategy to target cancer stem cells Lipid metabolism in cancer 지질 대사는 동화 작용 팔(지방산 합성)과 이화 작용 팔(β-산화)로 구성됩니다. 해당 분해는 포도당을 피루브산으로 변환하고, 피루브산은 미토콘드리아로 들어가 아세틸-CoA를 생성하고 옥살로아세테이트와 결합하여 시트르산을 형성합니다. 암 환경에서 저산소증 또는 해당 작용의 치료적 차단으로 인해 포도당 부족 현상이 발생하는 동안 암 세포의 바이오매스 및 에..

2021 https://www.mdpi.com/2072-6694/13/3/474/htm Lipid Metabolism in Oncology: Why It Matters, How to Research, and How to Treat Lipids in our body, which are mainly composed of fatty acids, triacylglycerides, sphingolipids, phospholipids, and cholesterol, play important roles at the cellular level. In addition to being energy sources and structural components of biological membrane www.mdpi.com..

2020 Alterations of Lipid Metabolism in Cancer: Implications in Prognosis and Treatment https://www.frontiersin.org/articles/10.3389/fonc.2020.577420/full Alterations of Lipid Metabolism in Cancer: Implications in Prognosis and Treatment Cancer remains the second leading cause of mortality worldwide. In the course of this multistage and multifactorial disease, a set of alterations takes place, w..

2021 https://lipidworld.biomedcentral.com/articles/10.1186/s12944-021-01593-8 How cancer cells remodel lipid metabolism: strategies targeting transcription factors - Lipids in Health and Disease Reprogramming of lipid metabolism has received increasing recognition as a hallmark of cancer cells because lipid dysregulation and the alteration of related enzyme profiles are closely correlated with o..

2020 https://rupress.org/jem/article/218/1/e20201606/211616/Lipid-metabolism-and-cancerLipid-metabolism-and Lipid metabolism and cancer | Journal of Experimental Medicine | Rockefeller University Press SREBP activation is regulated by sterol fluctuations in the ER. Cholesterol binds to SCAP, thereby disrupting the interaction between SCAP and COPII and retaining SREBP in the ER (Shimano and Sato..

2020 https://www.frontiersin.org/articles/10.3389/fonc.2020.605154/full The Lipid Metabolic Landscape of Cancers and New Therapeutic Perspectives Lipid metabolism reprograming, as a hallmark of malignancy, has received renewed interest in recent years in such areas as energy sources, cell membrane components, and signaling molecules involved in the rapid tumor growth and the adaptation to the tu..

2020 https://onlinelibrary.wiley.com/doi/full/10.1002/mco2.27 ******************************************************************** (a) 새로운 FA 합성 차단, FASN-올리스타트 ACLY-EGCG ACSS-Ranolazine 히드록시시트레이트(HCA) (b) FA 흡수 차단, 멜라토닌 (c) FA 이용 차단 ranolazine(협심증 치료) *콜레스테롤 Betulin Statins-피타바스타틴(리바로) Bitter-melon extract ---------------- ALACOX-2 억제제(세레브렉스) **최적의 치료를 위해서는 지질의 새로운 합성과 지질 흡수의 동시 억제가 필요할 수 있습니다. ..

2010 https://www.nps.org.au/australian-prescriber/articles/drug-interactions-with-complementary-medicines-1 Drug interactions with complementary medicines Table 1 Evidence-based complementary medicine interactions8,11,13,14 This table shows complementary medicines with at least one 'major' interaction. Complementary medicine Interacting drug Possible outcome Severity and level of evidence* Propo..

https://escop.com/interactions/ Table of herb-drug interactions based on the monographs of ESCOP - ESCOP The rational use of herbal medicinal preparations is based on the proof of quality, safety and efficacy. An important topic for health care professionals is the knowledge about interactions between herbal medicinal products (HMPs) and medications with synt escop.com 2022 Table of herb-drug in..

2019 https://www.vetfolio.com/learn/article/potential-drug-interactions-with-dietary-supplements VetFolio www.vetfolio.com Potential Drug Interactions with Dietary Supplements ****************************************************************